CBGa + CBDa + Botanicals


500mg CBG, 500mg CBD, 250mg CBG-A, 250mg CBD-A | 50mL (1.7 FL OZ)        

Aid regulation of immune homeostasis with plant-activated antibacterial, antimicrobial, antiviral, and antifungal properties. Enhanced with phytonutrients known to boost the body’s defenses and battle inflammation, this immune-supporting botanical blend has a dominantly spicy taste profile with subtle notes of citrus. Defend contains significantly higher levels of CBG-A and CBD-A, which can only be preserved with delicate processing techniques.

Infused with healing constituents, Defend includes astragalus, sea buckthorn oil, sweet orange, ginger, cardamom, cinnamon, and clove in addition to hemp-derived cannabinoids and a daily dose of Vitamin D.

A recent study found that the CBG-A and CBD-A can bind to proteins that affect wellness, thus potentially offering new avenues to support immune health.

Kokua Creations CBD is a full spectrum oil.

Full Spectrum

Kokua CBD is outdoor grown in Kentucky.

Outdoor Grown

Kokua creates their products in small batches in order to create less waste.

Small Batch

The extraction process used by Kokua is CO2 extraction.

CO2 Extracted

Products at Kokua are 3rd party tested.

3RD Party Tested

Kokua Creations CBD is a full spectrum oil.

full spectrum

Kokua CBD is outdoor grown in Kentucky.

Outdoor grown

Kokua creates their products in small batches in order to create less waste.

Small Batch

The extraction process used by Kokua is CO2 extraction.

CO2 extracted

Products at Kokua are 3rd party tested.

3RD party tested

Ancient Remedy for Holistic Immune Support

Nature is the best chemist. The immune-supporting ingredients are grown and extracted delicately to stay true to earth’s creations, preserving the plant’s biological integrity.

Administer the oil sublingually by dropping dose under the tongue. Hold for 60 seconds then swallow. Take up to two times per day. Individual results may vary.

This immune-supporting botanical blend has a dominantly spicy taste profile with subtle notes of citrus.

Coconut MCT Oil*, Full Spectrum Hemp Extract*, Sea Buckthorn Oil*, Astragalus*, Sweet Orange Essential Oil*, Ginger Essential Oil*, Cardamom Essential Oil*, Cinnamon Essential Oil*, Clove Essential Oil*,Vitamin D3


Defend dosage per mL:

10mg CBG

10mg CBD

5mg CBGa

5mg CBDa

1000 IU Vitamin D

A strong immune system is crucial to overall health as it plays a critical role in protecting the body against infections and diseases. The immune system is a complex network of cells, tissues, and organs that work together to protect the body from harmful invaders such as viruses, bacteria, and parasites. A healthy immune system also helps to prevent the growth of abnormal cells that can lead to cancer. 

The immune system also interacts with other systems of the body, such as the endocrine system, to help regulate various bodily functions. For example, the immune system can affect the release of hormones, which can impact mood, metabolism, and other bodily processes. 

Overall, a strong immune system is essential for maintaining overall health and preventing disease. Factors that can weaken the immune system include poor nutrition, chronic stress, lack of sleep, and exposure to toxins. Therefore, it is important to take steps to support the immune system, such as maintaining a healthy diet, getting enough rest, managing stress, and avoiding harmful substances.

Defend was developed as a powerful way to support the immune system via plant compounds. Every ingredient was selected to directly benefit and target immune health. Marie is passionate about holistic health, and she is very concerned about the growing number of peers being diagnosed with autoimmune conditions. She wants to offer support in any way possible, from intense research into causes and solutions to developing products, such a Defend, to support the body’s defense a little more with each dose.

Autoimmune issues are conditions where the immune system attacks healthy cells in the body, leading to a range of symptoms and potentially causing serious health issues. These types of conditions are increasing today, and a number of factors are thought to be responsible.

Stress is known to affect the immune system, and chronic stress can lead to a range of health problems, including autoimmune conditions. Diet can also play a role, as poor nutrition can lead to inflammation and other problems that impact the immune system. Additionally, gut health is thought to be important, as the gut is home to millions of bacteria that play a critical role in immune function. Poor gut health can lead to a range of health problems, including autoimmune conditions. Overall, it is important to take steps to manage stress, improve diet, and promote healthy gut health in order to maintain overall health and reduce the risk of developing autoimmune conditions. Marie’s product development specifically targets these various areas at risk. Ease supports relaxation and a healthy stress-response. Detox liquid chlorophyll targets gut health, reducing the internal toxic load, and alkalizing tissues. Defend directly targets immune health with antiviral, antifungal, and antibacterial compounds from powerful essential oils, such as clove and ginger.  

Cannabinoids reduce inflammation by interacting with the endocannabinoid system (ECS) and other pathways in the body that regulate immune responses.

The ECS is a complex system of receptors, endocannabinoids, and enzymes that plays a crucial role in regulating various physiological processes, including inflammation. The two main endocannabinoid receptors, CB1 and CB2, are found throughout the body, including in the central nervous system and immune cells.

CBD interacts with the ECS by modulating the activity of CB1 and CB2 receptors, as well as by inhibiting the breakdown of endocannabinoids such as anandamide, which can activate CB1 and CB2 receptors. This modulation of the ECS can help to reduce inflammation in various ways:

  1. Inhibiting cytokine production: Cytokines are small proteins that play a key role in regulating inflammation. Excessive production of cytokines can lead to chronic inflammation and tissue damage. CBD has been shown to inhibit the production of cytokines such as IL-1β, IL-6, and TNF-α, which are involved in many inflammatory conditions.
  2. Reducing oxidative stress: When the body is under stress, it produces reactive oxygen species (ROS) that can cause oxidative damage to cells. This oxidative stress can contribute to inflammation. Cannabinoids have been shown to have antioxidant properties that can reduce the production of ROS and protect cells from oxidative damage.
  3. Modulating immune cell activity: When the body is injured or under attack, immune cells are activated to fight off the invader and promote tissue repair. However, excessive immune cell activation can contribute to inflammation. CBD has been shown to modulate the activity of immune cells, including reducing the migration of immune cells to inflamed tissues.

In summary, CBD reduces inflammation by modulating the activity of the endocannabinoid system and other pathways involved in regulating immune responses. This modulation can lead to a reduction in cytokine production, oxidative stress, and immune cell activity, all of which contribute to inflammation.

Delicate compounds! Store at room temperature away from direct light. Do expose product to heat.

This product should be used only as directed on the label. Consult with a healthcare provider before use if you have a medical condition, use prescription medications, or are pregnant or nursing. The efficacy of this product or the ingredients have not been confirmed by FDA-approved research. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Full spectrum hemp products contain trace tetrahydrocannabinol (THC) amounting less than 0.3% on a dry weight basis.

Deep-Dive into Defend


Cannabinoids are molecules found in the hemp flower offering functional support by interacting with the cannabinoid receptors of our body’s endocannabinoid system. CBG-A is at the top of a cascade reaction that yields the three major cannabinoid lines CBG, CBD, and THC.


A dynamic blend of botanicals offers powerful plant-activated antibacterial, antimicrobial, antiviral, and antifungal properties. Defend’s phytonutrients from essential oils are known to boost the body’s defenses and battle inflammation.


The essence of functional botanicals infused with organic MCT oil to support the immune system. High in caprylic and capric acids, the antibacterial and antiviral carrier MCT oil can act as a natural antibiotic.


Full Spectrum Hemp
Coconut MCT Oil
Sea Buckthorn Oil
Ginger Essential Oil
Sweet Orange Essential Oil
Cardamom Essential Oil
Clove Essential Oil
Cinnamon Essential Oil
Vitamin D
How to use Kokua Creations CBD oil.

How To Use

1. Shake well before use.

2. Administer sublingually by dispensing Defend under the tongue.

3. Hold for at least 60 seconds.

4. Swallow and use up to two times per day for immune support.

Consistency is key to support immune health, and the benefits of Defend compound with cumulative use. Individual results may vary. Ingest up to two times per day. Defend can be taken in addition to a standard daily CBD dose.

With growing evidence of cannabinoids’ neuroprotective and anti-inflammatory properties, Defend is an essential addition to a proactive health approach.


300mg CBG, 300mg CBD, 150mg CBG-A, 150mg CBD-A


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CBGa + CBDa + Botanicals