Biome Balance
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Biome Balance

$48.00

Biome Balance | 30 acid-resistant capsules

30 Billion CFU Gut Health Probiotic

Whether your goal is to alleviate bloating, maintain bowel regularity, or provide your gut with daily support, Biome Balance makes nurturing your digestive health both effortless and effective. Each Biome Balance capsule contains 30 billion CFUs of beneficial bacteria, backed by proven efficacy and safety. This probiotic formula features 4 scientifically validated strains of friendly bacteria, including HN019®—a strain of Bifidobacterium lactis known for its protective effects on the intestinal lining. These capsules are designed to survive stomach acid and deliver live microorganisms where they’re needed most. To guarantee maximum freshness and potency, each capsule is individually sealed in an air-free blister pack, so you can experience the full benefits from the very first dose to the very last.

Ashwagandha

Turmeric

Vanilla Bean

Lemon Balm

Bergamot

Biome Balance

Biome Balance is a vegetarian, dairy- and gluten-free, four-strain probiotic totaling 30 billion CFU† per capsule. Each vegetarian capsule is sealed in nitrogen-purged aluminum blister packs to serve as protection from factors proven to compromise stability of probiotics such as heat, moisture, and oxygen. Biome Balance provides four researched strains of beneficial bacteria, including the extensively studied HN019® strain of Bifidobacterium lactis.

These live microorganisms have proven health benefits and well-established safety, and have been tested for epithelial cell adhesion and/or resistance to low pH. To further support resistance to low pH and the delivery of microorganisms to the small intestines, this supplement employs gastro-resistant capsules that help slow exposure of actives to stomach acid  and ensure more targeted release.

  • Promotes a Balanced Intestinal Microbiome
  • Helps Maintain a Healthy Intestinal Microecology
  • Supports Your Natural Immune Response
  • Supports Regular Bowel Function
  • Facilitates Lactose Digestion

Take one capsule with water daily, or as directed by your healthcare professional.

Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner. Do not use if tamper seal is damaged.

Active ingredients:

  • ZHOWARU® (Bifidobacterium lactis HN019®)
  • Lactobacillus acidophilus (Lactobacillus acidophilus La-14)
  • Lactiplantibacillus plantarum (Lactiplantibacillus plantarum Lp115)
  • Bifidobacterium longum (Bifidobacterium longum Bl-05)

Other ingredients: Capsule (hypromellose, gellan gum, and water), microcrystalline cellulose,
magnesium stearate, and silica.

Consult your healthcare professional prior to use. Individuals taking medication should discuss potential interactions with their healthcare professional. Do not use if tamper seal is damaged.

Before use, consult with your healthcare provider if you are nursing or pregnant, have any known allergies or medical conditions, or are taking any medication.

Keep closed in a cool, dry place out of reach of children.

Deep-Dive into Ease

Cannabinoids

Cannabinoids are molecules found in the hemp flower offering functional support by interacting with the cannabinoid receptors of our body’s endocannabinoid system. CBD and CBG are known to promote relaxation, ease tension, and combat inflammation.

Ashwagandha

A powerful adaptogen  known to assist the body’s ability to manage stress, ashwagandha is considered a grounding and nourishing herb, supportive to overall well-being.

Botanicals

The essence of functional botanicals infused with organic MCT oil to support rest and restoration. Ease features essential oils of turmeric, lemon balm, lemongrass, sweet orange, and bergamot.

Ingredients

Click on an Ingredient to learn more.

GABA

Gamma-aminobutyric acid (GABA) is a key inhibitory neurotransmitter in the brain that promotes relaxation, reduces stress, and improves sleep by calming neural activity. It helps alleviate anxiety, lowers stress hormones, and may enhance mood by balancing neurotransmitter levels. GABA also supports cognitive function, reduces muscle tension, and may aid in managing conditions like epilepsy and high blood pressure. Some studies suggest it could improve immunity and gut health. While the body produces GABA naturally, supplements or GABA-rich foods (like fermented products) may provide additional benefits.

GABA

Inositol

Inositol, a naturally occurring carbohydrate-like compound, offers multiple health benefits, particularly for mental and metabolic health. Often referred to as vitamin B8, it plays a key role in cell signaling and insulin sensitivity, making it beneficial for managing PCOS, reducing insulin resistance, and improving fertility. Inositol also supports mental well-being by alleviating symptoms of anxiety, depression, and panic disorders, as it influences serotonin and dopamine activity. Additionally, it may aid in reducing binge eating and promoting healthy sleep patterns. Found in foods like fruits, beans, and grains, inositol is also available as a supplement (commonly myo-inositol or D-chiro-inositol) for targeted therapeutic effects. Its calming and metabolic benefits make it a versatile nutrient for overall wellness.

Inositol

L-theanine

L-Theanine, an amino acid primarily found in tea leaves, offers multiple benefits for mental and physical well-being. It promotes relaxation without drowsiness by increasing alpha brain waves, which enhance calm focus and reduce stress. L-Theanine also helps lower anxiety, improves sleep quality, and supports cognitive function by boosting attention, memory, and reaction time. Additionally, it may enhance the effects of caffeine when combined, providing a balanced energy boost without jitters. Some research suggests it could strengthen immunity, lower blood pressure, and provide neuroprotective benefits. Naturally present in green and black tea, L-Theanine is also available as a supplement for those seeking its calming and cognitive-enhancing effects.

L-theanine

Taurine

Taurine is a sulfur-containing amino acid that plays a vital role in various bodily functions. It supports cardiovascular health by regulating blood pressure, improving heart function, and reducing the risk of heart disease. Taurine also enhances exercise performance by reducing muscle fatigue, increasing endurance, and aiding in recovery. It supports brain health by acting as a neuroprotective agent, improving cognitive function, and potentially reducing anxiety and depression. Additionally, taurine helps regulate blood sugar levels, promotes healthy vision, and supports liver and kidney function. Found naturally in meat, fish, and dairy, taurine is also a common ingredient in energy drinks and supplements, making it beneficial for overall health and wellness.

Taurine

Magnesium

Magnesium is an essential mineral involved in over 300 biochemical reactions in the body, making it crucial for overall health. It supports muscle and nerve function, helping to reduce cramps, spasms, and restless leg syndrome. Magnesium also promotes relaxation by regulating neurotransmitters, improving sleep quality, and reducing stress and anxiety. It plays a key role in heart health by maintaining normal blood pressure and supporting cardiovascular function. Additionally, magnesium aids in energy production, bone strength, and blood sugar regulation. Some studies suggest it may help with migraines, depression, and PMS symptoms. Found in foods like leafy greens, nuts, and whole grains, magnesium is also available as a supplement to address deficiencies and enhance well-being.

Magnesium

Deep-Dive into Biome Balance

Supplementation with probiotics has many mechanisms of action that benefit health, including but not limited to: (1) supporting metabolic activity, such as the production of short-chain fatty acids and vitamins, nutrient absorption, and digestion of lactose; (2) adhering to intestinal epithelial cells to help maintain a healthy balance of organisms in the intestinal tract; (3) helping to establish populations of good bacteria after disruption in balance; (4) supporting immune function; (5) promoting intestinal epithelial cell survival; (6) supporting healthy bowel function; and (7) degrading oxalates.*[1-8]

HOWARU® (Bifidobacterium lactis HN019®) Discovered in 1899, B lactis play a key role in the human microflora throughout a person’s life. Researchers have identified strain HN019® as having excellent probiotic potential based upon its ability to survive the transit through the human gastrointestinal tract, adhere to epithelial cells, and proliferate.[6] B lactis HN019® has been extensively studied, and its safety and effectiveness is well accepted.[7,8] To assess the impact of Bifidobacterium lactis HN019® supplementation on whole-gut transit
time in adults, 100 subjects were given daily doses for 14 days of 17.2 billion colony-forming units (CFU), 1.8 billion CFU, or placebo. Decreases in mean whole-gut transit time over the 14-day study
period were statistically significant in the high-dose group and the low-dose group, but not in the placebo group.[8] This level of dosing also supported other parameters of healthy GI function, as were
self-reported by patient survey.[8] In another study of preschool-age children, supplementing milk for one year with 1.9 x 10 CFU per day B lactis HN019® and 2.4 g/day of prebiotic oligosaccharides supported both healthy iron status and weight gain.[9] In a randomized, double-blind, placebo-controlled human dietary intervention study in elderly subjects (>60 yrs.), supplementary B lactis HN019® resulted in statistically significant increases in the beneficial organisms bifidobacteria and lactobacilli.*[10]

Lactobacillus acidophilus (Lactobacillus acidophilus La-14) This common inhabitant of the human mouth, intestinal tract, and vagina, is also found in some traditional fermented milks (e.g., kefir) and is widely used in probiotic foods and supplements. It has a history of safe human consumption. The L acidophilus La-14 strain is of human origin and has been identified as a type A1 L acidophilus. L acidophilus shows excellent adhesion to human epithelial cell-lines.*[11,12] 

Lactiplantibacillus plantarum (Lactiplantibacillus plantarum Lp115) This bacteria was isolated from plant material and is abundantly present in lactic acid-fermented foods, such as olives and sauerkraut. In vitro studies have shown that L plantarum strain Lp-115 has excellent adhesion to epithelial cell lines.[13] In addition, L plantarum is resistant to low pH conditions and survives the presence of bile at duodenal concentrations.*[13,14] 

Bifidobacterium longum (Bifidobacterium longum Bl-05) The B longum Bl-05 strain is well accepted as safe for human consumption. B longum is resistant to low pH and bile salts and is well suited to the intestinal environment.*[14]

1. Vanderpool C, Yan F, Polk DB. Mechanisms of probiotic action: Implications for therapeutic applications in inflammatory bowel diseases. Inflamm Bowel Dis. 2008 Nov;14(11):1585-96. [PMID: 18623173]
2. Abratt VR, Reid SJ. Oxalate-degrading bacteria of the human gut as probiotics in the management of kidney stone disease. Adv Appl Microbiol. 2010;72:63- 87. [PMID: 20602988]
3. Masood MI, Qadir MI, Shirazi JH, et al. Beneficial effects of lactic acid bacteria on human beings. Crit Rev Microbiol. 2011 Feb;37(1):91-98. [PMID: 21162695] 4. Turroni S, Vitali B, Bendazzoli C, et al. Oxalate consumption by lactobacilli: evaluation of oxalyl-CoA decarboxylase and formyl-CoA transferase activity in Lactobacillus acidophilus. J Appl Microbiol. 2007 Nov;103(5):1600-09. [PMID: 17953571]
5. Shu Q, Lin H, Rutherfurd KJ, et al. Dietary Bifidobacterium lactis (HN019) enhances resistance to oral Salmonella typhimurium infection in mice. Microbiol Immunol. 2000;44(4):213-22. [PMID: 10832963]
6. Gopal P, et al. Effects of the consumption of Bifidobacterium lactis HN019 (DR10TM) and galacto-oligosaccharides on the microflora of the gastrointestinal tract in human subjects. Nutr. Res. 2003;23:1313-28. http://www. daniscosupplements.com/clinical-study-bibliography.html. Accessed June 24,
2011.
7. Danisco. Clinical study bibliography & abstracts. HOWARU Bifido – Bif. lactis HN019. http://www.daniscosupplements.com/clinical-study-bibliography.html. Accessed June 24, 2011.
8. Waller PA, Gopal PK, Leyer GJ, et al. Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults. Scand J Gastroenterol. 2011 Sep;46(9):1057-64. [PMID: 21663486]
9. Sazawal S, Dhingra U, Hiremath G, et al. Effects of Bifidobacterium lactis HN019 and prebiotic oligosaccharide added to milk on iron status, anemia, and growth among children 1 to 4 years old. J Pediatr Gastroenterol Nutr. 2010 Sep;51(3):341-46. [PMID: 20601905]
10. Ahmed M, Prasad J, Gill H, et al. Impact of consumption of different levels of Bifidobacterium lactis HN019 on the intestinal microflora of elderly human subjects. J Nutr Health Aging. 2007 Jan-Feb;11(1):26-31. [ 17315077]
11. Greene JD, Klaenhammer TR. Factors involved in adherence of lactobacilli to human Caco-2 cells. Appl Environ Microbiol. 1994 Dec;60(12):4487-94. [PMID: 7811085]
12. Kleeman EG, Klaenhammer TR. Adherence of Lactobacillus species to human fetal intestinal cells. J Dairy Sci. 1982 Nov;65(11):2063-69. [PMID: 7153393].
13. Collado MC, Meriluoto J, Salminen S. Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus. Lett Appl Microbiol. 2007 Oct;45(4):454-60. [PMID: 17897389]
14. Ding WK, Shah NP. Acid, bile, and heat tolerance of free and microencapsulated probiotic bacteria. J Food Sci. 2007 Nov;72(9):M446-50. [PMID: 18034741]

How to use Kokua Creations CBD oil.

How To Use

1. Shake well before use.

2. Administer sublingually by dispensing Ease Drops under the tongue.

3. Hold for at least 60 seconds.

4. Swallow and enjoy daily support for focus, clarity, mood support, sleep, relaxation and recovery.

Consistency is key to support overall health, and the benefits of Ease Drops compound with cumulative use. Some may experience immediate effects, while others can take up to 30 days of consistent use. Individual results may vary. Ingest up to two times per day.

With growing evidence of cannabinoids’ neuroprotective properties, Ease is an essential addition to a proactive health approach. 

Strength

300mg CBG, 300mg CBD, 150mg CBG-A, 150mg CBD-A

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$48.00